Automated Estimation of Brain Volume in Multiple Sclerosis with BICCR
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چکیده
Neurodegenerative diseases are often associated with loss of brain tissue volume. Our objective was to develop and evaluate a fully automated method to estimate cerebral volume from magnetic resonance images (MRI) of patients with multiple sclerosis (MS). In this study, MRI data from 17 normal subjects and 68 untreated MS patients was used to test the method. Each MRI volume was corrected for image intensity non-uniformity, intensity normalized, brain masked and tissue classified. The classification results were used to compute a normalized metric of cerebral volume based on the Brain to IntraCranial Capacity
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تاریخ انتشار 2001